NICE Recommends Once-Weekly Insulin That Could Cut Diabetes Jabs by 85%

What happened, why it matters, and what to know

NICE, the body that decides which treatments the NHS in England and Wales can offer, has recommended a new once-weekly insulin injection for adults with type 2 diabetes. The drug is called insulin efsitora alfa, sold under the brand name Onswik, made by Eli Lilly. In final draft guidance published around 20-21 August 2026, NICE said people who currently inject a daily basal insulin could switch to this weekly version instead, cutting injections from 365 a year to just 52, an 85% reduction. It still needs a UK marketing licence from the MHRA before it can be prescribed on the NHS, expected in the coming months. Around 4.6 million people in the UK are living with diagnosed diabetes, and about 90% have type 2 diabetes. NICE specifically highlighted that this change could make the biggest difference for frailer people, those with sight loss, limited hand movement, or learning disabilities, and anyone who relies on a carer for injections. Fewer jabs means fewer chances to miss a dose and less day-to-day disruption. NICE's decision was based on trials comparing insulin efsitora alfa against insulin degludec and insulin glargine, showing it controls blood glucose just as effectively as the daily alternatives - a finding about equivalence, not superiority. Not everyone currently on daily insulin will be a suitable candidate for the weekly version; people with frailty, changeable eating patterns, or acute kidney problems may need extra caution when switching. This is exactly the kind of change that can genuinely improve medication adherence for people who find daily routines hard to keep up. At Qurexa, we see every day how the practical side of managing a long-term condition, remembering doses and getting repeat prescriptions when needed, matters as much as the medicine itself. If you or someone you care for currently injects daily insulin for type 2 diabetes, don't change anything yet - this medicine is not currently available on the NHS. The useful action today is to ask your GP, practice nurse, or diabetes team at your next review whether this option might suit you once available, and mention any difficulties with daily injections. Source: NICE, "Weekly insulin jab could cut injections from 365 a year to just 52", 20 August 2026, nice.org.uk. This article is for general information and does not replace advice from a doctor, pharmacist or other qualified healthcare professional.